Education:

• Licence en Chimie, Université Libre de Bruxelles, 1969
• PhD, Université Libre de Bruxelles, 1973
• Agrégation de l'Enseignement Supérieur, Université Libre de Bruxelles, 1988

Research interests:

• Modeling the molecular regulatory mechanisms of biological rhythms: Circadian rhythms and related disorders of the sleep-wake cycle, segmentation clock, cell cycle, metabolic oscillations, oscillations and waves of cyclic AMP in Dictyostelium cells, oscillations and waves of calcium, pulsatile hormone secretion (GnRH, insulin), frequency encoding of pulsatile signals, oscillatory shuttling of transcription factors, complex oscillatory phenomena, transitions between periodic and chaotic behavior.
• Threshold phenomena in enzyme regulation through phosphorylation-dephosphorylation ("zero-order ultrasensitivity").
• Coexistence of multiple steady states (bistability).