At UCSD, Andrew is an Adjunct Professor in the Dept of Computer Science and Engineering. Effective June 20, 2011, he also serves as a Professor in the Department of Computer Science at the University of Chicago, and a Senior Scientist at Argonne National Laboratories.

From 2005-2010, Andrew served as Vice President and Director of Intel Research. From 2003-2005, he created and served as Founding Director of the UCSD Center for Networked Systems. From 1998-2005, Andrew was the SAIC Chair Professor in Computer Science and Engineering at University of California, San Diego and from 1990-1998, a Professor in Computer Science at the University of Illinois. Andrew is a Fellow of the Association for Computing Machinery (ACM), the Institute for Electrical and Electronics Engineers (IEEE), and the American Association for the Advancement of Science (AAAS).