Mitochondria calcium signalling in cell life and death

author: Rosario Rizzuto, CRUI - Conferenza dei Rettori delle Università italiane
published: April 23, 2019,   recorded: March 2019,   views: 0
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Description

The Mitochondrial Calcium Uniporter (MCU) mediates Ca2+ transport inside the organelle matrix, thus shaping global calcium signals and controlling either aerobic metabolism or cell death through apoptosis. The molecular elucidation and in vivo targeting of the MCU complex is now revealing new information on the role of mitochondrial Ca2+ signaling in health and disease

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