Folding Funnels in Energy Landscapes

author: Konstantin Klemm, Bioinformatics, University of Leipzig
published: Nov. 30, 2007, recorded: October 2007, views: 3636

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Description

Local minima and the saddle points separating them in the energy landscapeare known to dominate the dynamics of biopolymer folding. Here weintroduce a notion of a 'folding funnel' that is concisely defined interms of energy minima and saddle points, while at the same time conformingto a notion of a 'folding funnel' as it is discussed in the protein foldingliterature.

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