The Bayesian Group-Lasso for Analyzing Contingency Tables

author: Sudhir Raman, Department of Computer Science, University of Basel
published: Aug. 26, 2009,   recorded: June 2009,   views: 3922
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Description

Group-Lasso estimators, useful in many applications, suffer from lack of meaningful variance estimates for regression coefficients. To overcome such problems, we propose a full Bayesian treatment of the Group-Lasso, extending the standard Bayesian Lasso, using hierarchical expansion. The method is then applied to Poisson models for contingency tables using a highly efficient MCMC algorithm. The simulated experiments validate the performance of this method on artificial datasets with known ground-truth. When applied to a breast cancer dataset, the method demonstrates the capability of identifying the differences in interactions patterns of marker proteins between different patient groups.

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