This talk will cover recent innovations in large-scale machine learning and their applications on massive, real-world data sets at Verizon. These applications power new revenue generating products and services for the company and are hosted on a massive computing and storage platform known as Orion. We will discuss the architecture of Orion and the underlying algorithmic framework. We will also cover some of the real-world aspects of building a new organization dedicated to creating new product lines based on data science.