This paper is focused on the main aspects of an experience that took place from September to December 2013. It deals with the implementation of a course developed by the OportUnidad project, referred to as Principles and Strategies of Open Education for a Teaching Innovation (PREA, for its acronym in Spanish). This experience allowed assessing the proposal and resources created throughout the project, as well as their benefits for Latin American universities that might want to use open education. In fact, the analysis of this paper is mainly aimed not only at assessing the implementation of the course according to the opinion of the moderators and participants from 47 higher education institutions from Latin America, but also identifying improvement areas for future course editions, which will be available to the global community.