Constrained Hidden Markov Models for Population-based Haplotyping

author: Niels Landwehr, University of Freiburg
published: Feb. 25, 2007,   recorded: June 2006,   views: 332
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Description

Analysis of genetic variation in human populations is critical to the understanding of the genetic basis for complex diseases. Although genomes of several species have been sequenced, it is still too expensive to sequence genomes of several individuals to analyze genetic variation. Furthermore, most of the genome is invariant among individuals.

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