Freshman Organic Chemistry

CHEM 125 - Freshman Organic Chemistry

author: J. Michael McBride, Department of Chemistry, Yale University
recorded by: Yale University
released under terms of: Creative Commons Attribution No Derivatives (CC-BY-ND)

This is the first semester in a two-semester introductory course focused on current theories of structure and mechanism in organic chemistry, their historical development, and their basis in experimental observation. The course is open to freshmen with excellent preparation in chemistry and physics, and it aims to develop both taste for original science and intellectual skills necessary for creative research.

Course Homepage: http://oyc.yale.edu/chemistry/freshman-organic-chemistry/

Course features at Open Yale courses page:

Exams:


11234 views, 46:40 Lecture 1 - How Do You Know? Freshman Organic ChemistryLecture 1 - How Do You Know? Freshman Organic Chemistry J. Michael McBride J. Michael McBride 1 comment	5145 views, 50:12 Lecture 2 - Force Laws, Lewis Structures and ResonanceLecture 2 - Force Laws, Lewis Structures and Resonance J. Michael McBride J. Michael McBride	3291 views, 45:02 Lecture 3 - Double Minima, Earnshaw's Theorem and Plum-PuddingsLecture 3 - Double Minima, Earnshaw's Theorem and Plum-Puddings J. Michael McBride J. Michael McBride	2791 views, 50:01 Lecture 4 - Coping with Smallness and Scanning Probe MicroscopyLecture 4 - Coping with Smallness and Scanning Probe Microscopy J. Michael McBride J. Michael McBride	6724 views, 47:09 Lecture 5 - X-Ray DiffractionLecture 5 - X-Ray Diffraction J. Michael McBride J. Michael McBride
3183 views, 51:10 Lecture 6 - Seeing Bonds by Electron Difference DensityLecture 6 - Seeing Bonds by Electron Difference Density J. Michael McBride J. Michael McBride	3634 views, 49:17 Lecture 7 - Quantum Mechanical Kinetic EnergyLecture 7 - Quantum Mechanical Kinetic Energy J. Michael McBride J. Michael McBride	3396 views, 49:50 Lecture 8 - One-Dimensional Wave FunctionsLecture 8 - One-Dimensional Wave Functions J. Michael McBride J. Michael McBride	3028 views, 49:35 Lecture 9 - Chladni Figures and One-Electron AtomsLecture 9 - Chladni Figures and One-Electron Atoms J. Michael McBride J. Michael McBride	2933 views, 48:33 Lecture 10 - Reality and the Orbital ApproximationLecture 10 - Reality and the Orbital Approximation J. Michael McBride J. Michael McBride
2830 views, 49:26 Lecture 11 - Orbital Correction and Plum-Pudding MoleculesLecture 11 - Orbital Correction and Plum-Pudding Molecules J. Michael McBride J. Michael McBride	2732 views, 50:34 Lecture 12 - Overlap and Atom-Pair BondsLecture 12 - Overlap and Atom-Pair Bonds J. Michael McBride J. Michael McBride	2513 views, 49:43 Lecture 13 - Overlap and Energy-MatchLecture 13 - Overlap and Energy-Match J. Michael McBride J. Michael McBride	2528 views, 47:36 Lecture 14 - Checking Hybridization Theory with XH3Lecture 14 - Checking Hybridization Theory with XH3 J. Michael McBride J. Michael McBride	4045 views, 47:11 Lecture 15 - Chemical Reactivity: SOMO, HOMO, and LUMOLecture 15 - Chemical Reactivity: SOMO, HOMO, and LUMO J. Michael McBride J. Michael McBride
2744 views, 50:08 Lecture 16 - Recognizing Functional GroupsLecture 16 - Recognizing Functional Groups J. Michael McBride J. Michael McBride	2760 views, 41:43 Lecture 17 - Reaction Analogies and Carbonyl ReactivityLecture 17 - Reaction Analogies and Carbonyl Reactivity J. Michael McBride J. Michael McBride	3077 views, 51:20 Lecture 18 - Amide, Carboxylic Acid and Alkyl LithiumLecture 18 - Amide, Carboxylic Acid and Alkyl Lithium J. Michael McBride J. Michael McBride	2795 views, 47:09 Lecture 19 - Oxygen and the Chemical Revolution (Beginning to 1789)Lecture 19 - Oxygen and the Chemical Revolution (Beginning to ... J. Michael McBride J. Michael McBride 1 comment	2597 views, 50:00 Lecture 20 - Rise of the Atomic Theory (1790-1805)Lecture 20 - Rise of the Atomic Theory (1790-1805) J. Michael McBride J. Michael McBride
2465 views, 49:21 Lecture 21 - Berzelius to Liebig and Wöhler (1805-1832) Lecture 21 - Berzelius to Liebig and Wöhler (1805-1832) J. Michael McBride J. Michael McBride	2611 views, 49:14 Lecture 22 - Radical and Type Theories (1832-1850)Lecture 22 - Radical and Type Theories (1832-1850) J. Michael McBride J. Michael McBride	2549 views, 48:46 Lecture 23 - Valence Theory and Constitutional Structure (1858)Lecture 23 - Valence Theory and Constitutional Structure (1858) J. Michael McBride J. Michael McBride	2520 views, 50:14 Lecture 24 - Determining Chemical Structure by Isomer Counting (1869)Lecture 24 - Determining Chemical Structure by Isomer Counting (1869) J. Michael McBride J. Michael McBride	2973 views, 49:01 Lecture 25 - Models in 3D Space (1869-1877); Optical Isomers Lecture 25 - Models in 3D Space (1869-1877); Optical Isomers J. Michael McBride J. Michael McBride
2919 views, 48:26 Lecture 26 - Van't Hoff's Tetrahedral Carbon and ChiralityLecture 26 - Van't Hoff's Tetrahedral Carbon and Chirality J. Michael McBride J. Michael McBride	2591 views, 51:35 Lecture 27 - Communicating Molecular Structure in Diagrams and WordsLecture 27 - Communicating Molecular Structure in Diagrams and Words J. Michael McBride J. Michael McBride	3627 views, 47:29 Lecture 28 - Stereochemical Nomenclature; Racemization and ResolutionLecture 28 - Stereochemical Nomenclature; Racemization and Resolution J. Michael McBride J. Michael McBride	2574 views, 50:18 Lecture 29 - Preparing Single Enantiomers and the Mechanism of Optical RotationLecture 29 - Preparing Single Enantiomers and the Mechanism of ... J. Michael McBride J. Michael McBride	2966 views, 50:42 Lecture 30 - Esomeprazole as an Example of Drug Testing and UsageLecture 30 - Esomeprazole as an Example of Drug Testing ... J. Michael McBride J. Michael McBride
2521 views, 48:52 Lecture 31 - Preparing Single Enantiomers and Conformational EnergyLecture 31 - Preparing Single Enantiomers and Conformational Energy J. Michael McBride J. Michael McBride	3063 views, 46:17 Lecture 32 - Stereotopicity and Baeyer Strain TheoryLecture 32 - Stereotopicity and Baeyer Strain Theory J. Michael McBride J. Michael McBride	2643 views, 47:52 Lecture 33 - Conformational Energy and Molecular MechanicsLecture 33 - Conformational Energy and Molecular Mechanics J. Michael McBride J. Michael McBride	2702 views, 49:17 Lecture 34 - Sharpless Oxidation Catalysts and the Conformation of CycloalkanesLecture 34 - Sharpless Oxidation Catalysts and the Conformation of ... J. Michael McBride J. Michael McBride	2695 views, 48:41 Lecture 35 - Understanding Molecular Structure and Energy through Standard BondsLecture 35 - Understanding Molecular Structure and Energy through Standard ... J. Michael McBride J. Michael McBride
2714 views, 47:50 Lecture 36 - Bond Energies, the Boltzmann Factor and EntropyLecture 36 - Bond Energies, the Boltzmann Factor and Entropy J. Michael McBride J. Michael McBride	3451 views, 47:43 Lecture 37 - Potential Energy Surfaces, Transition State Theory and Reaction MechanismLecture 37 - Potential Energy Surfaces, Transition State Theory and ...

Reviews and comments:

1 J. Terry Fuqua, April 27, 2011 at 8:49 p.m.:

Happened onto this site & am having a ball! First chemistry lecture I've had since Vanderbilt 1960. VERY novel approach to freshman chemistry.

But I do miss smelling the aldehydes & ketones.

2 Jennifer, July 10, 2012 at 9:34 p.m.:

Is it just me or are the pages for exams not working?

http://videolectures.net/yalechem125f...

3 Davor (Publication Manager), July 12, 2012 at 6:02 p.m.:

@Jennifer - you can`t see the pages for exams, because the links were pointing on Yale`s webpage. They removed those, so the links don`t work anymore. In order to avoid confusion we just removed them also on our side.

4 Burhan Saglam, February 15, 2013 at 8:52 p.m.:

Prof.J. Michael McBride,
Department of Chemistry,
Yale University

Dear McBride,

I have got two projects about cancer therapy and organic total synthesis,hence I am wishing a PhD research scholarship from you and Yale University's Board.

Yours faithfully,

Burhan Saglam
Tel:00 90 536 737 6283

Address:
Memduhiye M.,Gelincik S.,No:5
55700 Havza-Samsun
TURKEY

5 McBride, January 30, 2021 at 5:28 p.m.:

Many course materials including exams are available through:

http://chem125.webspace.yale.edu

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Freshman Organic Chemistry

CHEM 125 - Freshman Organic Chemistry

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