Both physics and biology are characterized by tremendous progress and breakthroughs. We witnessed the birth of the theories of general relativity, quantum mechanics and the first attempts to design a Grand Unifying Theory, each of them deeply rooted in a ‘quasi-platonic’ belief in the consistency of mathematics. The invention of the transistor triggered an exponential proliferation of technology that has been tremendously beneficial for society. Similarly, in biology, we start understanding the basic mechanisms of life and its Darwinian evolution. Through mathematics and technology, biology has become an information driven discipline facing a tsunami of data, providing us with a better understanding of health and disease. Gradually, we start designing life and living organisms. In this talk, I will explore three utopian visions. 1. One day, we will truly ‘understand’ the unreasonable effectiveness of mathematics in physics. 2. One day, we will design and build life from scratch. 3. One day, we will build artificial brains with emerging consciousness.