Genetic variation in gene regulation
published: Oct. 6, 2014, recorded: December 2013, views: 4
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Genetic variants that impact gene expression play a central role in the genetics of complex traits and in evolution. Yet the precise links between genetic variation and changes in gene regulation are poorly understood and it remains very difficult to predict which variants have regulatory effects in any given cell type. In this talk I will describe work we have done on identifying genetic variants that impact gene expression and understanding the primary mechanisms by which such variants act.
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