Lecture 31 - Preparing Single Enantiomers and Conformational Energy
recorded by: Yale University
published: June 10, 2010, recorded: November 2008, views: 2521
released under terms of: Creative Commons Attribution No Derivatives (CC-BY-ND)
See Also:
Download yalechem125f08_mcbride_lec31_01.mov (Video - generic video source 528.8 MB)
Download yalechem125f08_mcbride_lec31_01.flv (Video 617.1 MB)
Download yalechem125f08_mcbride_lec31_01_640x360_h264.mp4 (Video 146.3 MB)
Related content
Report a problem or upload files
If you have found a problem with this lecture or would like to send us extra material, articles, exercises, etc., please use our ticket system to describe your request and upload the data.Enter your e-mail into the 'Cc' field, and we will keep you updated with your request's status.
Description
After mentioning some legal implications of chirality, the discussion of configuration concludes using esomeprazole as an example of three general methods for producing single enantiomers. Conformational isomerism is more subtle because isomers differ only by rotation about single bonds, which requires careful physico-chemical consideration of energies and their relation to equilibrium and rate constants. Conformations have their own notation and nomenclature. Curiously, the barrier to rotation about the C-C bond of ethane was established by measuring its heat capacity.
Problem sets/Reading assignment:
Reading assignments, problem sets, PowerPoint presentations, and other resources for this lecture can be accessed from Professor McBride's on-campus course website, which was developed for his Fall 2008 students. Please see Resources section below.
Resources:
Link this page
Would you like to put a link to this lecture on your homepage?Go ahead! Copy the HTML snippet !
Write your own review or comment: